2013年于中山大学取得化学学士学位，2019年在美国犹他大学取得博士学位（导师为Peter J. Stang院士），之后在德国马克斯-普朗克高分子研究所进行博士后研究（洪堡学者 ，合作导师为Tanja Weil教授）。2023年1月加入湖南大学化学化工学院，任教授，并加入分子成像实验室。主要研究方向为基于分子自组装的生物医用材料，如成像探针材料、药物递送材料和组织功能材料等。共发表SCI收录论文35篇，其中以第一（含共同）或通讯作者身份发表论文14篇，包括PNAS（3篇）, J. Am. Chem. Soc.（5篇）和Angew. Chem.（1篇），总被引用超过2500次。

Zhixuan was born and raised in Nanning, China. He studied chemistry at Sun Yat-sen University and obtained his B.S. in 2013. He then moved to the University of Utah in Salt Lake City, USA, where he completed his Ph.D. research on supramolecular coordination complexes with emergent functions under the supervision of Professor Peter J. Stang. In March 2019, he moved to Germany and joined the group of Professor Tanja Weil at the Max Planck Institute for Polymer Research as a postdoctoral researcher. He was awarded the Humboldt Research Fellowship in March 2020. In 2023, Zhixuan started his independent research career as a Professor at the College of Chemistry and Chemical Engineering, Hunan University, where his research focuses on supramolecular polymers with biomedical applications.

Email: zzhou@hnu.edu.cn

2023.01-至今，湖南大学化学化工学院，教授，岳麓学者

2019.05-2023.01，德国马克斯-普朗克研究所，洪堡学者博士后(合作导师:Tanja Weil教授与David Ng博士)

2013.08-2019.05，美国犹他大学，化学，博士（导师：Peter J. Stang教授，美国科学院院士，中国科学院外/籍院士）

2009.09-2013.06，中山大学，化学，理学学士

第一（含共同）或通讯作者身份发表论文：(#:共同第一作者*:通讯作者)

Publications as first/corresponding author: (#: equal contributions *: corresponding author)

[1]“In Situ Assembly of Platinum (II)-Metallopeptide Nanostructures Disrupts Energy Homeostasis and Cellular Metabolism”Zhou, Z.; Maxeiner, K.; Moscariello, P.; Xiang, S.; Wu, Y.; Whitfield, C. J.; Xu, L.; Kaltbeitzel, A.; Han, S.; Mücke, D.; Qi, H.; Wagner, M.; Kaiser, U.; Landfester, K.; Lieberwirth, I.; Ng, D. Y. W.*; Weil, T.* J. Am. Chem. Soc. 2022, 144, 12219-12228. DOI:10.1021/jacs.2c03215

[2]“Self-assembled Pt(II) Metallacycles Enable Precise Cancer Combination Chemotherapy”Zhang, P.; Zhou, Z.*; Long, W.; Yan, Y.; Li, Y.; Fu, T.; Liu, Y.; Zhao, Z.*; Tan, W.*; Stang, P. J.* Proc. Natl. Acad. Sci. U. S. A. 2022, 119, e2202255119. DOI:10.1073/pnas.2202255119

[3]“Polymer Chemistry in Living Cells”Zhou, Z.; Maxeiner, K.; Ng, D. Y. W.*; Weil, T.* Acc. Chem. Res. 2022, 55, 2998-3009. DOI:10.1021/acs.accounts.2c00420

[4]“Light-emitting Self-assembled Metallacages”Zhao, J. #; Zhou, Z.#; Li, G.; Stang, P. J.*; Yan, X.*Natl. Sci. Rev. 2021, 8, nwab045. DOI:10.1093/nsr/nwab045

[5]“Trackable Supramolecular Fusion: Cage to Cage Transformation of Tetraphenylethylene‐Based Metalloassemblies”Li, G.#; Zhou, Z.#; Yuan, C.; Guo, Z.; Liu, Y.; Zhao, D.; Liu, K.; Zhao, J.; Tan, H.; Yan, X.*Angew. Chem. Int. Ed. 2020, 59, 10013-10017. DOI:10.1002/anie.202000078

[6]“A Self-assembled Ru-Pt Metallacage as a Lysosome-Targeting Photosensitizer for Two-Photon Photodynamic Therapy”Zhou, Z.#; Liu, J.#; Huang, J.; Rees, T. W.; Wang, Y.; Wang, H.; Li, X.; Hui, C.*; Stang, P. J.*Proc. Natl. Acad. Sci. U. S. A. 2019, 116, 20296-20302. DOI:10.1073/pnas.1912549116

[7]“Designed Conformation and Photoluminescence Properties of Self-Assembled Phenazine-Cored Platinum (II) Metallacycles”Zhou, Z.#; Chen, D.-G.#; Saha, M. L.; Wang, H.; Li, X.; Chou, P.-T.*; Stang, P. J.*J. Am. Chem. Soc. 2019, 141, 5535-5543. DOI:10.1021/jacs.9b01368

[8]“Understanding the Effects of Coordination and Self-Assembly on an Emissive Phenothiazine”Zhou, Z.; Cory, C. E.; Bo, S.; Li, X.; Stang, P. J.*; Cook, T. R.*J. Am. Chem. Soc. 2019, 141, 3717-3722. DOI:10.1021/jacs.9b00363

[9]“Heterometallic Ru-Pt Metallacycle for Two-Photon Photodynamic Therapy”Zhou, Z.#; Liu, J.#; Rees, T. W.; Wang, H.; Li, X.; Hui, C.*; Stang, P. J.*Proc. Natl. Acad. Sci. U. S. A. 2018, 115, 5664-5669. DOI:10.1073/pnas.1802012115

[10]“Immobilizing Tetraphenylethylene into Fused Metallacycles: Shape Effects on Fluorescence Emission”Zhou, Z.; Yan, X.*; Saha, M. L.*; Zhang, M.; Wang, M.; Li, X.; Stang, P. J.* J. Am. Chem. Soc. 2016, 138, 13131-13134. DOI:10.1021/jacs.6b07173

[11]“Engineering Functionalization in a Supramolecular Polymer: Hierarchical Self-Organization of Triply Orthogonal Non-Covalent Interactions on a Supramolecular Coordination Complex Platform”Zhou, Z.; Yan, X.*; Cook, T. R.; Saha, M. L.; Stang, P. J.*J. Am. Chem. Soc. 2016, 138, 806-809. DOI:10.1021/jacs.5b12986

[12]Self-Assembly of Porphyrin-Containing Metalla-Assemblies and Cancer Photodynamic Therapy”Jiang, X.#; Zhou, Z.#; Yang, H.; Shan, C.; Yu, H.; Wojtas, L.; Zhang, M.; Mao, Z.*; Wang, M.*; Stang, P. J.*Inorg. Chem. 2020, 59, 7380-7388. DOI:10.1021/acs.inorgchem.9b02775

[13]“Self-Assembled Amphiphilic Janus Double Metallacycle”Wang, W.#; Zhou, Z.#; Zhou, J.; Shi, B.; Song, B.; Li, X.; Huang, F.*; Stang, P. J.*Inorg. Chem. 2019, 58, 7141-7145. DOI:10.1021/acs.inorgchem.9b01036

[14]“Design and Synthesis of 3,5-Diaryl-4,5-Dihydro-1H-Pyrazoles as New Tyrosinase Inhibitors”Zhou, Z.; Zhuo, J.; Yan, S.; Ma, L.*Bioorg. Med. Chem. 2013, 21, 2156-2162. DOI:10.1016/j.bmc.2012.12.054

2024国家海外高层次人才青年项目

2022马普所Kalkhof-Rose高分子科学奖

Kalkhof Rose Polymer Science Award, Max Planck Institute for Polymer Research

2020洪堡博士后研究奖金

Humboldt Research Fellowship for postdoctoral researchers

2019国家优秀自费留学生奖学金

Chinese government award for outstanding self-financed students abroad