陈卓，化学生物传感全国重点实验室、湖南大学环境科学与工程学院、化学化工学院、分子科学与生物医学实验室（MBL）二级教授，博士生导师。主持国家自然科学基金杰出青年基金、优秀青年基金等项目，入选多项国内高层次人才计划，目前已在Nat. Biotechnol.、Nat. Comput. Sci.、Nat. Commun.、JACS.、Angew Chemie.、Adv.Mater.、Anal.Chem.等学术期刊上发表论文130余篇，授权发明专利16项。承担过多项国家自然科学基金、国家重大科学仪器设备开发专项子项目、国家重点基础研究发展计划课题等科研基金。主要研究方向为纳米生物化学分析方法、环境分析与健康，包括光谱分析化学、基于功能材料的胃部疾病诊疗等研究。

联系方式：zhuochen@hnu.edu.cn

2024.05 - 至今，湖南大学环境科学与工程学院，院长，教授，博士生导师

2012.04 - 至今，湖南大学化学化工学院，教授，博士生导师

2010.11 - 2012.04，湖南大学生物学院，研究员，博士生导师

2006.10 - 2010.09，美国斯坦福大学化学系，博士后

2001.09 - 2006.07，北京大学化学与分子工程学院，理学博士

1997.09 - 2001.07，浙江大学理学院化学系，理学学士

部分主持项目：

2023年至2027年，主持国家杰出青年科学基金项目；

2022年至2025年，主持国家重点研发计划项目课题；

2018年至2020年，主持湖南省自然科学基金杰出青年基金项目；

2016年至2018年，主持国家优秀青年科学基金项目；

2012年至2015年，主持科技部国家重大科学仪器设备开发专项子项。

科研论文

[1]Yurong Chen, Shen Wang, Yaonan Wang*, Jianxu Mao Lizhu Liu, Xiaoxu Cao, Zhuo Chen*, Hui Zhang*, Self-optimized spectral distance for low-light high-throughput Raman hyperspectral imaging, Nature Computational Science 2026, doi.org/10.1038/s43588-026-00957-3.

[2]Zhiwei Yin, Ling Li, Qiang Zhang, Xiaoshen Zhang, Rui Shi, Xin Xia, Zhaoxin Wang, Shengkai Li, Mao Ye, Yanlan Liu, Weihong Tan, Zhuo Chen*. PerC B‐Cells Activation via Thermogenetics‐Based CXCL12 Generator for Intraperitoneal Immunity Against Metastatic Disseminated Tumor Cells. Advanced Materials. 2025, 37(10), 2411731.

[3]Yuqi Cheng, Lingjin Zhao, Yijing Wen, Zhen Ren, Jiayu Zeng, Rui Shi, Xinqi Cai*, Qian Dong*, Long Chen, Changwei Lin, Zhuo Chen*. In vivo spatiotemporal acquisition of metabolic vibrational signatures for unraveling gastric ulcer genesis. Biomaterials, 2025, 322, 123383.

[4]Liang Zhang, Lufeng Zhang, Chundi Wei, Shen Wang, Jieqiong Xu, Zhiwei Yin, Yanxia Yang, Shengkai Li, Qian Dong, Zhengyu Deng, Long Chen, Chunyan Liu*, Ding Ding*, Zhuo Chen*. Constructing Ultra-Strong SERS Tags in the Cellular Raman-Silent Region by Orthogonal Array Testing Strategy. Analytical Chemistry. 2024, 96(22), 9051-9059.

[5]Hui Deng, Yi Zhang, Xinqi Cai, Zhiwei Yin, Yanxia Yang, Qian Dong, Ye Qiu, Zhuo Chen*. Dual-Targeted Graphitic Cascade Nanozymes for Recognition and Treatment of Helicobacter pylori. Small. 2024, 20(14), 2306155.

[6]Li Zhang, Qian Dong, Yumin Hao, Zihan Wang, Wenjuan Dong, Yang Liu, Yueping Dong, Hongpeng Wu, Shaomin Shuang, Chuan Dong*, Zhuo Chen*, Xiaojuan Gong*. Drug-Primed Self-Assembly of Platinum-Single-Atom Nanozyme to Regulate Cellular Redox Homeostasis Against Cancer. Advanced Science. 2023, 10(30), 2302703.

[7]Jieqiong Xu, Jing Guo, Shengkai Li, Yanxia Yang, Weiming Lai, Phouphien Keoingthong, Shen Wang, Liang Zhang, Qian Dong, Zebing Zeng, Zhuo Chen*. Dual Charge Transfer Generated from Stable Mixed-Valence Radical Crystals for Boosting Solar-to-Thermal Conversion. Advanced Science. 2023, 10(21), 2300980.

[8]Yanxia Yang, Hongxiu Bu, Yiting Xu, Shengkai Li, Jieqiong Xu, Xin Xia, Zhiwei Yin, Long Chen, Zhuo Chen*, Weihong Tan. Heat Confinement Aerogel Enables Supramagnetothermal Effect for Triggering Nitric Oxide Generation. Nano Letters. 2022, 22, 8339−8345.

[9]Zhiwei Yin, Rui Shi, Xin Xia, Ling Li, Yanxia Yang, Shengkai Li, Jieqiong Xu, Yiting Xu, Xinqi Cai, Shen Wang, Zhangkun Liu, Tianhuan Peng, Ying Peng, Hua Wang, Mao Ye, Yanlan Liu, Zhuo Chen*, Weihong Tan. An Implantable Magnetic Vascular Scaffold for Circulating Tumor Cell Removal In Vivo. Advanced Materials. 2022, 34, 2207870.

[10]Xin Xia, Zhiwei Yin, Yanxia Yang, Shengkai Li, Linlin Wang, Xinqi Cai, Yiting Xu, Chao Ma, Ye Qiu, Zhuo Chen*, Weihong Tan. In Situ Upregulating Heat Shock Protein 70 via Gastric Nano-Heaters for the Interference of Helicobacter pylori Infection. ACS Nano. 2022, 16(9), 14043–14054.

[11]Jieqiong Xu, Qian Chen, Shengkai Li, Jiachao Shen, Phouphien Keoingthong, Liang Zhang, Zhiwei Yin, Xinqi Cai, Zhuo Chen*, Weihong Tan. Charge-Transfer Cocrystal via a Persistent Radical Cation Acceptor for Efficient Solar-Thermal Conversion. Angewandte Chemie-International Edition. 2022, 61, e202202571.

[12]Lufeng Zhang, Liang Zhang, Hui Deng, Huan Li, Wentao Tang, Luyao Guan, Ye Qiu, Michael J. Donovan, Zhuo Chen*, Weihong Tan. In vivoActivation of pH-responsive Oxidase-like Graphitic Nanozymes for Selective Killing of Helicobacter pylori. Nature Communications. 2021, 12, 2002.

[13]Qiong Wu, Chengcheng Liu, Cheng Cui*, Long Li, Lu Yang, Yuan Liu, Hoda Safari Yazd, Shujuan Xu, Xiang Li, Zhuo Chen*, Weihong Tan*. Plasmon coupling in DNA-assembled silver nanoclusters. Journal of the American Chemical Society. 2021, 143(36), 14573.

[14]Ren Cai, Dan Yang, Keng-Te Lin, Yifan Lyu, Bowen Zhu, Zhen He, Lili Zhang, Yusuke Kitamura, Liping Qiu, Xigao Chen, Yuliang Zhao, Zhuo Chen*, Weihong Tan*. Generalized Preparation of Two-Dimensional Quasi-nanosheets via Self-assembly of Nanoparticles. Journal of the American Chemical Society. 2019, 141(4), 1725-1734.

[15]Qian Dong, Xuewei Wang, Xiaoxiao Hu, Langqiu Xiao, Liang Zhang, Lijuan Song, Minglu Xu, Yuxiu Zou, Long Chen, Zhuo Chen*, Weihong Tan*. Simultaneous application of photothermal therapy and anti-inflammatory prodrug using Pyrene-aspirin-loaded Gold nanorod-graphitic-nanocapsules. Angewandte Chemie International Edition. 2018, 57, 177-181.

[16]Yunjie Li, Xiaoxiao Hu, Ding Ding, Yuxiu Zou, Yiting Xu, Xuewei Wang, Yin Zhang, Long Chen, Zhuo Chen*, Weihong Tan. In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules. Nature Communications. 2017, 8, 15653.

[17]Zhi-Ling Song, Zhuo Chen*, Xia Bian, Li-Yi Zhou, Ding Ding, Hao Liang, Yu-Xiu Zou, Shan-Shan Wang, Long Chen, Chao Yang, Xiao-Bing Zhang*, Weihong Tan*. Alkyne-functionalized superstable graphitic Silver nanoparticles for Raman imaging. Journal of the American Chemical Society. 2014, 136(39), 13558.

科研专利成果

[1]陈卓，徐逸婷，夏昕，蔡芯琪，杨艳霞，董倩“一种利用核磁共振成像检测胃酸pH值的胶囊及其制备方法”

[2]陈卓，张良，王昚，许洁琼“一种石墨烯包裹的钴铂复合纳米材料及其制备工艺与应用”

[3]陈卓，许洁琼，尹志威，张良，董倩“一种有机NIR-Ⅱ光热转换膜及其制备方法和应用”

[4]陈卓，邹玉秀，谭蔚泓，黄澌琪“一种SERS试纸条及其制备方法、应用”

[5]陈卓，刘芳，谭蔚泓，张良“一种表面增强拉曼散射基底及其制备方法”

[6]陈卓，程振乾，谭蔚泓，聂祥坤，“一种磁性纳米光催化剂”

部分奖项：

[1]2023年，湖南省“优秀研究生导师”；

[2]2022年，浙江大学沈善洪杰出青年学者奖获得者；

[3]2020年，国家自然科学二等奖（荧光探针性能调控与生物成像应用基础研究，第4完成人）；

[4]2018年，湖南省部自然科学一等奖（高性能荧光探针构建与生物成像应用，第3完成人）；

[5]2013年，教育部新世纪优秀人才支持计划入选者；

[6]2013年，湖南省湖湘青年科技创新创业平台培养对象；