教授
姚瑞枫,清华大学生物学博士,现任湖南大学“岳麓学者”特聘教授、生物学院副院长。长期从事植物激素作用机理及蛋白质结构与功能研究。研究工作以第一作者或通讯作者(含共同)发表在Nature、Nature Communications、Cell Research、Molecular Plant、Plant Biotechnology Journal、Plant Physiology、Plant Journal、《中国科学-生命科学》等国内外主流期刊,并受邀在Trends in Plant Science、Current Opinion in Plant Biology、《植物学报》等发表综述或热点评。
部分成果入选中国高校十大科技进展、中国生命科学领域十大进展、国际生物信号转导领域重要突破。主持国家高层次人才计划青年项目、国家重点研发计划青年科学家项目、国家重点研发计划子课题、国家自然科学基金面上项目、湖南省科技创新领军人才项目等国家级或省部级课题。
作为秘书长成功组织第3届国际独脚金内酯大会(共同主席:李家洋院士、谢道昕院士),受邀为PNAS、Nature Plants、Nature Communications、Plant Cell、Molecular Plant、Science Advances、Science Signaling等知名期刊审稿,于国际植物学大会、国际独脚金内酯大会、全国蛋白质组学大会、北京大学现代农学院等学术会议或机构作学术报告。
联系方式:ryao@hnu.edu.cn
2022.05 -至今,湖南大学生物学院,党委委员、副院长
2021.03 - 2022.05,湖南大学生物学院,院长助理、系主任
2018.11 -至今,湖南大学生物学院,教授、博导、化学生物传感与计量学国家重点实验室PI、岳麓学者
2016.11 - 2018.11,清华大学生命科学学院(清华-北大生命科学联合中心),助理研究员、博士后(合作导师:谢道昕 院士)
2010.09 - 2016.10,清华大学生命科学学院,博士研究生(导师:谢道昕 院士;联培导师:饶子和 院士)
2006.09 - 2010.06,华中科技大学生命科学与技术学院,本科生(班主任、导师:余龙江 教授)
[1]国家重点研发计划青年科学家项目(2022YFF1002000),主持,在研(2022-2027)
[2]国家重点研发计划项目(2021YFA1300400)子课题,主持,在研(2021-2026)
[3]国家自然科学基金面上项目(32470340),主持,在研(2025-2028)
[4]国家自然科学基金面上项目(32270334),主持,在研(2023-2026)
[5]国家自然科学基金面上项目(32070321),主持,在研(2021-2024)
[6]湖南省科技创新领军人才(2023RC1050),主持,在研(2023-2026)
[7]湖湘青年英才支持计划(2019RS2019),主持,结题(2019-2022)
[8]湖南省优秀青年科学基金(2020JJ3007),主持,结题(2020-2022)
[9]中国科协“青年人才托举工程”(YESS20160148),主持,结题
[10]中国博士后科学基金,特别资助(2017T100063),主持,结题
[11]中国博士后科学基金,面上一等资助(2017M610078),主持,结题
[12]清华大学-北京大学生命科学联合中心博士后基金(特等),主持,结题
[13]国家自然科学基金重点项目(31630085),项目组主要成员,结题
[14]国家自然科学基金重点项目(31230008),项目组主要成员,结题
[15]国家重点研发计划“蛋白质机器与生命过程调控”重点专项(2016YFA05005000),参加,结题
[16]国家转基因生物新品种培育重大专项(2014ZX08011006),参加,结题
科研著作:
[1]Strigolactone: Signaling and Functions in Plants. Co-Editors: Ruifeng Yao, Tadao Asami, Catherine Rameau, Steven Smith. Frontiers in Plant Science (2021). ISSN 1664-8714; ISBN 978-2-83252-015-4; DOI: 10.3389/978-2-83252-015-4
[2]Strigolactone signaling complex formation in yeast: A paradigm for studying hormone-induced receptor interaction with multiple downstream proteins;DOI: 10.1016/bs.mie.2022.05.006;A chapter to Carotenoids: Biological functions of carotenoids and apocarotenoids in natural and artificial systems edited by Eleanore T. Wurtzel;2022;ISBN:9780323913515; Methods in Enzymology, Elsevier
发表论文:
[1]Yao Ruifeng*, Ming Z*, Yan L*, Li S*, Wang F, Ma S, Yu C, Yang M, Chen L, Chen LH, Li Y, Yan C, Miao D, Sun Z, Yan J, Sun Y, Wang L, Chu J, Fan S, He W, Deng H, Nan F, Li J, Rao Zihe#, Lou Zhiyong#, Xie Daoxin#. DWARF14 is a non-canonical hormone receptor for strigolactone. Nature (2016) 536: 469-473. (IF5-yr = 54.4012,ESI highly cited paper & ESI hot paper)
[2]Yao Ruifeng*, Wang F*, Ming Z, Du X, Chen L, Wang Y, Zhang W, Deng H, Xie Daoxin#. ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds. Cell Research (2017) 27: 838-841. (IF5-yr = 36.3996)
[3]Xiang H*, Yao Ruifeng*, Quan T, Wang F, Chen L, Du X, Zhang W, Deng H, Xie Daoxin#, Luo Tuoping#. Simple β-lactones are potent irreversible antagonists for strigolactone receptors. Cell Research (2017) 27: 1525-1528. (IF5-yr = 36.3996)
[4]Li H*, Yao Ruifeng*, Ma S*, Hu S, Li S, Wang Y, Yan C, Xie D, Yan J. Efficient ASK-assisted system for expression and purification of plant F-box proteins. Plant Journal (2017) 92: 736-743. (IF5-yr = 7.1000)
[5]Yao Ruifeng*, Wang L*, Li Y*, Chen L*, Li S, Du X, Wang B, Yan J, Li Jiayang#, Xie Daoxin#. Rice DWARF14 acts as an unconventional hormone receptor for strigolactone. Journal of Experimental Botany (2018) 69: 2355-2365. (IF5-yr = 6.7996)
[6]Yao Ruifeng*, Chen L*, Xie Daoxin#. Irreversible strigolactone recognition: a non-canonical mechanism for hormone perception. Current Opinion in Plant Biology (2018) 45:155-161. (IF5-yr = 8.6000)
[7]Yan J*, Yao Ruifeng*, Chen L, Li S, Gu M, Nan F, Xie Daoxin#. Dynamic perception of jasmonates by the F-box protein COI1. Molecular Plant (2018) 11: 1237-1247. (IF5-yr = 21.3993)
[8]Yao Ruifeng, Li J, Xie D#. Recent advances in molecular basis for strigolactone action. Science China Life Sciences (2018) 61: 277-284. (IF5-yr = 7.300)
[9]Wang Y*, Yao Ruifeng*,#, Du X, Guo L, Chen L, Xie D#, S Steven#. Molecular basis for high ligand sensitivity and selectivity of strigolactone receptors in Striga. Plant Physiology (2021) 185:1411-1428. (IF5-yr = 7.600)
[10]W Xiao*, S Hu*, X Zou, R Cai, R Liao, X Lin, Ruifeng Yao#, X Guo#. Lectin receptor-like kinase LecRK-VIII.2 is a missing link in MAPK signaling-mediated yield control. Plant Physiology (2021) 187:303-320. (IF5-yr = 7.600)
[11]A Hu, Q Zhao, L Chen, J Zhao, Y Wang, K Feng, L Wu, M Xie, X Zhou, L Xiao, Z Ming#, M Zhang#, Ruifeng Yao#. Identification of conserved and divergent strigolactone receptors in sugarcane reveals a key residue crucial for plant branching control. Frontiers in Plant Science (2021) 12:747160. (IF5-yr = 5.300)
[12]P Wang#, E Limpens#, Ruifeng Yao#. Orchestrating plant direct and indirect phosphate uptake pathways. Trends in Plant Science (2022) doi: 1016/j.tplants.2021.12.005. (IF5-yr = 20.100)
[13]Dawei Wang*, Zhili Pang*, Haiyang Yu, Benjamin Thiombiano, Aimee Walmsley, Shuyi Yu, Yingying Zhang, Tao Wei, Lu Liang, Jing Wang, Xin Wen, Harro J. Bouwmeester#, Ruifeng Yao#, Zhen Xi#. Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds. Nature Communications (2022) DOI: 10.1038/s41467-022-31710-9. (IF5-yr = 16.100)
[14]Liu P*, Xie T*, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Ruifeng Yao, Cahoon EB, Dunn TM, Gong X#. Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex. Science Advances (2023) 9:eadg0728. (IF5-yr = 13.700)
[15]Chen L*, Fang Y*, Zhou X, Zhang M, Ruifeng Yao#, Tian B#. Magnetic DNA Nanomachine for On-Particle Cascade Amplification-Based Ferromagnetic Resonance Detection of Plant MicroRNA. Analytical Chemistry (2023) 95:5411-5418. (IF5-yr = 6.500)
[16]W Xiao*, S Hu*, K Yu*, Y Li, R Cai, D Xie, H Zhou, Z Guo, S Liu, X Zou, S Ye, A Guo, Ruifeng Yao#, H Zhao#, X Guo#. Fine-tuning of MPK6/3 phosphorylation by a lectin receptor-like kinase LecRK-VIII.2 regulates seed development. Plant Biotechnology Journal (2023) 21(12):2414-2416. (IF5-yr = 11.6000)
[17]Fang Y, Yang Y, Yao Z, Lei X, Dong Z, Zhang M#, Ruifeng Yao#, Tian B#. On-Particle Hyperbranched Rolling Circle Amplification-Scaffolded Magnetic Nanoactuator Assembly for Ferromagnetic Resonance Detection of MicroRNA. ACS Sensors (2023) doi: 10.1021/acssensors.3c01967. (IF5-yr = 8.4001)
[18]Li, Q.*, Yu, H.*, Chang, W.*, Chang, S., Guzmán, M., Faure, L., Wallner, E.-S., Yan, H., Greb, T., Wang, L., Yao Ruifeng#, Nelson, D. C#. SMXL5 attenuates strigolactone signaling in Arabidopsis thaliana by inhibiting SMXL7 degradation. Molecular Plant (2024) doi: 10.1016/j.molp.2024.03.006 (IF5-yr = 21.3993)
[19]Chen, P., Huang, P., Yu, H., Yu, H., Xie, W., Wang, Y., Zhou, Y., Chen, L., Zhang, M.#, and Yao Ruifeng#. Strigolactones shape the assembly of root-associated microbiota in response to phosphorus availability. Msystems (2024) 9, e01124-01123. (IF5-yr = 6.1004)
[20]C Xue, M Zhang#, and Ruifeng Yao#. Gapless biosynthetic pathway enables sustainable paclitaxel production. Trends in Plant Science (2024) doi: 10.1016/j.tplants.2024.05.005. (IF5-yr = 20.100)
[21]J Bai, X Lei, J Liu, Y Huang, L Bi, Y Wang, J Li, H Yu, S Yao, L Chen, BJ Janssen, KC Snowden#, M Zhang#, and Ruifeng Yao#. Molecular mechanism of strigolactone receptor DWARF14-regulated flowering in Arabidopsis. The Plant Cell 2024 DOI: 10.1093/plcell/koae248 (IF5-yr = 11.1000)
[1]2023-2026,湖南省科技创新领军人才项目(“三尖计划”拔尖人才)
[2]2020-2023,国家级高层次人才计划青年项目入选者
[3]2022,湖南大学“青年教工党员示范岗”
[4]2019-2022,湖湘青年英才
[5]2016-2018,中国科协“青年人才托举工程”入选者
[6]2017,第19届国际植物学大会Outstanding Student Award
[7]2017,北京市优秀毕业生(研究生)
[8]2017,清华大学优秀博士毕业生
[9]2017,清华大学优秀博士学位论文(一等奖)
[10]2016-2018,清华大学--北京大学生命科学联合中心博士后特等资助
[11]2016,清华大学结构生物学高精尖创新中心博士生奖学金(卓越奖)
[12]2014,国家奖学金(博士研究生)
[13]2014,拜耳作物科学奖学金
[14]2006-2010,华中科技大学优秀毕业生等荣誉或奖励十余项
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