湖南大学生命医学交叉研究院教授、博士生导师，抗真菌药物耐药机制及其靶向干预课题组负责人。

联系方式：zhaofengyan@hnu.edu.cn

2020.11-现在 湖南大学，生命医学交叉研究院，教授

2019.11-2020.9 霍华德休斯医学研究所，博士后

2010.9-014.7 中国科学技术大学，生物科学，理学学士

2014.9-2019.7 清华大学，生物学，理学博士

[1]国家自然科学基金面上项目，2024-2027，主持，在研

[2] 国家自然科学基金青年科学基金项目，2022-2024，主持，结题

发表论文：

[1] Chenchen Pei*, Hui Sun*, Yinliang Qi*, Xiaomei Li*, Zhixiong Fang*, Manjuan Tang, Rujing Zhang, Zhaofeng Yan#, Meng Yin#. Structural insights into the secretin complex of a type IVb pilus system. Nature Communications, 2025, 16(1): 9136.

[2] Hui Zhang*, Dihan Zheng*, Qiurong Wu, Nieng Yan, Han Peng, Qi Hu, Ying Peng, Zhaofeng Yan, Zuoqiang Shi, Chenglong Bao#, Mingxu Hu#. CryoPROS: correcting misalignment caused by preferred orientation using AI-generated auxiliary particles. Nature Communications, 2025, 16(1): 4565.

[3] Ying Peng*, Yan Lu*, Hui Sun*, Jinying Ma*, Xiaomei Li*, Xiaodan Han*, Zhixiong Fang, Junming Tan, Yingchen Qiu, Tingting Qu, Meng Yin#, Zhaofeng Yan#. Cryo-EM structures of Candida albicans Cdr1 reveal azole-substrate recognition and inhibitor blocking mechanisms. Nature Communications, 2024,15(1): 7722.

[4] Zhaofeng Yan*, Meng Yin*, Jianan Chen*, Xueming Li#. Assembly and substrate recognition of curli biogenesis system. Nature Communications, 2020,11(1): 241.

[5] Meng Yin*, Zhaofeng Yan*, Xueming Li#. Architecture of type VI secretion system membrane core complex. Cell Research, 2019, 29(3): 251-253.

[6] Meng Yin*, Zhaofeng Yan*, Xueming Li#. Structural insight into the assembly of the type II secretion system pilotin-secretin complex from enterotoxigenic Escherichia coli. Nature Microbiology, 2018, 3(5): 581-587.

[7] Zhaofeng Yan*, Meng Yin*, Dandan Xu, Yongqun Zhu#, Xueming Li#. Structural insights into the secretin translocation channel in the type II secretion system. Nature Structural & Molecular Biology, 2017, 24(2): 177-183.